Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 5/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 5/20 | 0.32 |
| ▸ | DAO | P14920 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906963 | 0.85 | L3MBTL1 (0.36) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8420336 | 0.81 | BCAT2 (0.31) | BCAT2BCAT1 | |
| SCHEMBL8420772 | 0.80 | SMN1; SMN2 (0.35) | BCAT2BCAT1DAO | |
| SCHEMBL9023675 | 0.79 | TRPV4 (0.33) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8381949 | 0.78 | L3MBTL1 (0.34) | BCAT2BCAT1PGR | |
| SCHEMBL6984955 | 0.76 | BCAT2 (0.36) | PDE4APDE4BPDE4CPDE4DBCAT2 | |
| SCHEMBL7029446 | 0.76 | GPBAR1 (0.33) | BCAT2BCAT1 | |
| SCHEMBL7010249 | 0.75 | KMT2A (0.36) | BCAT2BCAT1PGR | |
| SCHEMBL8594988 | 0.75 | L3MBTL1 (0.34) | BCAT2BCAT1PGR | |
| SCHEMBL7027406 | 0.74 | GPBAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946521-A1 | METHOD FOR PRODUCING 3-AMINO-1-PHENYL-URACIL DERIVATIVES BY MAKING 3,4-DIHYDRO-2H-1,3-OXYAZINE-2,4 DION DERIVATIVES TO REACT WITH HYDRAZINE (ADDUCTS) | BAYER AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027068-A1 | METHOD FOR PRODUCING 3-AMINO-1-PHENYL-URACIL DERIVATIVES BY MAKING 3,4-DIHYDRO-2H-1,3-OXYAZINE-2,4 DION DERIVATIVES TO REACT WITH HYDRAZINE (ADDUCTS) | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |