Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029466 | 1.00 | SMN1; SMN2 (0.31) | SMN1; SMN2NOTUMMCL1ALOX15HTT | |
| SCHEMBL7024628 | 0.81 | GABRB3 (0.41) | — | |
| SCHEMBL7024622 | 0.81 | GABRB3 (0.41) | — | |
| SCHEMBL7023972 | 0.71 | GABRP (0.47) | SMN1; SMN2 | |
| SCHEMBL7023977 | 0.71 | GABRP (0.47) | SMN1; SMN2 | |
| SCHEMBL7549474 | 0.64 | GABRP (0.40) | — | |
| SCHEMBL7549480 | 0.64 | GABRP (0.40) | — | |
| SCHEMBL7920622 | 0.63 | NPFFR2 (0.39) | NOTUMHTT | |
| SCHEMBL8169905 | 0.63 | NPFFR2 (0.39) | NOTUMHTT | |
| SCHEMBL7027480 | 0.62 | GABRB3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638956-B2 | Pesticidal 1-arylpyrazoles | RHONE-POULENC, INC. | 2003-10-28 | — | — | US | claimed |