SCHEMBL7029574

SCHEMBL7029574

CCN(CC)c1ccccc1-c1ccc(Cc2ccc(-c3ccccc3N(CC)CC)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.37
AR P10275 2/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
TSHR P16473 2/20 0.36
CYP1A2 P05177 2/20 0.36
LTA4H P09960 2/20 0.36
CYP2D6 P10635 2/20 0.36
HTT P42858 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HRH3 Q9Y5N1 1/20 0.35
CALM1 P0DP23 1/20 0.34
RAB9A P51151 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4817859 0.84 NR3C1 (0.46) ARNR3C1PGRTSHRKMT2A
SCHEMBL16559113 0.83 CRHR1 (0.42) CNR2ARNR3C1PGRTSHR
SCHEMBL8576661 0.77 KIF11 (0.46) TSHRCYP1A2CYP2C19KDM4EALDH1A1
SCHEMBL11344279 0.77 NQO1 (0.47) TSHRLTA4HRAB9AMEN1GAA
SCHEMBL16577651 0.77 NR3C1 (0.41) ARNR3C1PGRTSHRKMT2A
Bromide SCHEMBL5900325 0.76 MAPK11 (0.50) ARNR3C1PGRTSHRCYP1A2
SCHEMBL27961980 0.75 ESR2 (0.44) CNR2ARCYP1A2ALDH1A1CYP3A4
SCHEMBL10387576 0.73 ALDH1A1 (0.43) CNR2TSHRHTTRAB9AMEN1
SCHEMBL6299189 0.72 TSHR (0.46) CNR2ARNR3C1PGRTSHR
SCHEMBL31718395 0.72 TSHR (0.46) CNR2ARNR3C1PGRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615164-B1 Photoconductive imaging member and its production process XEROX CORP (US) 2003-01-22 EP disclosed
EP-0577245-B1 Photogenerating azo pigments XEROX CORP (US) 1998-12-02 EP disclosed
EP-0554110-B1 Processes for the preparation of photogenerating compositions XEROX CORP (US) 1997-05-07 EP disclosed
EP-0559392-B1 Photoconductive imaging members with ladder polymers XEROX CORP (US) 1997-05-07 EP disclosed
US-5449582-A Pigment-Lewis acid complex XEROX CORPORATION (US) 1995-09-12 US disclosed
US-5405724-A Coating photogenerating film containing complex dispersed on a substrate, drying and washing with protic solvent to remove lewis acid, drying coated substrate XEROX CORPORATION (US) 1995-04-11 US disclosed
US-5384223-A Styrene-vinylpyridine block polymer XEROX CORPORATION (US) 1995-01-24 US disclosed
US-5362586-A Electrostatic process for duplicating original having discrete areas of black and, as highlight, red or blue by forming electrostatic image on photoreceptor with conductive substrate and two photogenerating layers; developing with charged toner XEROX CORPORATION (US) 1994-11-08 US disclosed
EP-0615164-A2 Photoconductive imaging members and processes thereof XEROX CORPORATION (US) 1994-09-14 EP disclosed
US-5281503-A Multilayer element with disazo pigments and charge generating layer XEROX CORPORATION (US) 1994-01-25 US disclosed
EP-0093616-A2 Protective coatings for photoresponsive devices XEROX CORPORATION (US) 1983-11-09 EP disclosed
US-4410616-A Multi-layered ambipolar photoresponsive devices for electrophotography XEROX CORPORATION (US) 1983-10-18 US disclosed
EP-0014061-B1 PHOTOSENSITIVE IMAGING MEMBER AND METHOD XEROX CORPORATION (US) 1983-04-06 EP disclosed
US-4371600-A Release overcoat for photoresponsive device XEROX CORPORATION (US) 1983-02-01 US disclosed
US-4291110-A ELECTROGRAPHY XEROX CORPORATION (US) 1981-09-22 US disclosed
US-4281054-A Overcoated photoreceptor containing injecting contact XEROX CORPORATION (US) 1981-07-28 US disclosed
US-4275133-A Electrophotographic imaging processes utilizing adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1981-06-23 US disclosed
EP-0014061-A1 Photosensitive imaging member and method XEROX CORPORATION (US) 1980-08-06 EP disclosed
US-4181772-A Adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1980-01-01 US disclosed
US-4123269-A Electrostatographic photosensitive device comprising hole injecting and hole transport layers XEROX CORPORATION (US) 1978-10-31 US disclosed