Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701476 | 0.93 | CES2 (0.36) | CES2CES1MAPTNAAA | |
| SCHEMBL701320 | 0.81 | ALDH1A1 (0.33) | ALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL699496 | 0.81 | TSHR (0.35) | PTGS2CES2CES1TSHRPCSK9 | |
| Octane SCHEMBL18395350 | 0.76 | DNM1 (0.44) | CES2CES1TSHRLTA4HNAAA | |
| Octane SCHEMBL23754774 | 0.74 | DNM1 (0.42) | CES2CES1LTA4HALDH1A1NAAA | |
| SCHEMBL10434550 | 0.74 | LTA4H (0.39) | CES2CES1TSHRPCSK9LTA4H | |
| SCHEMBL699721 | 0.74 | SLC6A2 (0.36) | TSHRALDH1A1LMNA | |
| SCHEMBL10357730 | 0.73 | TP53 (0.41) | CES2CES1TSHRPCSK9LTA4H | |
| SCHEMBL25312239 | 0.72 | ALDH1A1 (0.34) | ALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL21693993 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688424-B1 | PHOSPHONIUM BORATE COMPOUND AND METHOD OF USING THE SAME | HOKKO CHEM IND CO (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-8604249-B2 | Process for producing phosphonium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-12-10 | — | — | US | disclosed |
| US-8124809-B2 | Process for producing phosphonium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20110237799-A1 | Process for Producing Phosphonium Borate Compound, Novel Phosphonium Borate Compound, and Method of Using the Same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110166389-A1 | Process for Producing Phosphonium Borate Compound, Novel Phosphonium Borate Compound, and Method of Using the Same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-07-07 | — | — | US | disclosed |
| US-7728176-B2 | Process for producing phosphonium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20090305877-A1 | Process for producing phosphonium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20070098616-A1 | Process for producing phosponium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1688424-A1 | PROCESS FOR PRODUCING PHOSPHONIUM BORATE COMPOUND, NOVEL PHOSPHONIUM BORATE COMPOUND, AND METHOD OF USING THE SAME | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2006-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166389-A1 | Process for Producing Phosphonium Borate Compound, Novel Phosphonium Borate Compound, and Method of Using the Same | CA4, EPB41, MAPK4 | PTGS2 3825/4885CES2 4765/4885CES1 4714/4885 |
| US-20110237799-A1 | Process for Producing Phosphonium Borate Compound, Novel Phosphonium Borate Compound, and Method of Using the Same | EPB41, CA4, RBBP4 | PTGS2 3914/4885CES2 4797/4885CES1 4745/4885 |
| US-20090305877-A1 | Process for producing phosphonium borate compound, novel phosphonium borate compound, and method of using the same | PHOSPHO1, BRI3BP, CA4 | PTGS2 4551/4885CES2 4428/4885CES1 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.