SCHEMBL7030474

SCHEMBL7030474

CCCCOc1ccc(C(=O)N[C@@H](CNC(=O)c2ccc(OCCNC(=N)N)cc2O)C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.43
F2 P00734 1/20 0.43
PLAU P00749 1/20 0.43
PLAT P00750 1/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 1/20 0.43
ITGB3 P05106 5/20 0.41
ITGAV P06756 1/20 0.41
ITGA2B P08514 4/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
SPHK1 Q9NYA1 2/20 0.40
CA2 P00918 1/20 0.40
ITGB1 P05556 1/20 0.39
ITGA4 P13612 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7034005 0.92 F10 (0.43) F10F2PLAUPLATITGB3
SCHEMBL7034864 0.92 CA2 (0.43) F10F2PLAUPLATITGB3
SCHEMBL7032350 0.92 MEN1 (0.46) F10F2PLAUPLATITGB3
SCHEMBL7037813 0.91 ITGB3 (0.49) F10F2PLAUPLATITGB3
SCHEMBL7032861 0.90 ITGB3 (0.44) F10F2PLAUPLATITGB3
SCHEMBL7037930 0.90 ITGB3 (0.42) F10F2PLAUPLATITGB3
SCHEMBL7035472 0.90 PTPN1 (0.43) F10F2PLAUPLATPPARG
SCHEMBL7030442 0.90 ITGB3 (0.47) F10F2PLAUPLATITGB3
SCHEMBL7035668 0.90 ITGB3 (0.43) F10F2PLAUPLATITGB3
SCHEMBL7032531 0.89 ITGB3 (0.42) F10F2PLAUPLATITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR F10 2695/4885F2 4014/4885PLAU 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.