SCHEMBL7034005

SCHEMBL7034005

CCc1ccc(C(=O)N[C@@H](CNC(=O)c2ccc(OCCNC(=N)N)cc2O)C(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.43
F2 P00734 1/20 0.43
PLAU P00749 1/20 0.43
PLAT P00750 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ITGB3 P05106 6/20 0.41
ITGAV P06756 1/20 0.41
ITGA2B P08514 5/20 0.41
CTSL P07711 1/20 0.40
CTSS P25774 1/20 0.40
MAPT P10636 3/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA2 P00918 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030474 0.92 F10 (0.43) F10F2PLAUPLATITGB3
SCHEMBL7032350 0.91 MEN1 (0.46) F10F2PLAUPLATITGB3
SCHEMBL7034864 0.91 CA2 (0.43) F10F2PLAUPLATITGB3
SCHEMBL7037813 0.90 ITGB3 (0.49) F10F2PLAUPLATITGB3
SCHEMBL7037930 0.90 ITGB3 (0.42) F10F2PLAUPLATITGB3
SCHEMBL7035472 0.90 PTPN1 (0.43) F10F2PLAUPLATKDM4E
SCHEMBL7032531 0.88 ITGB3 (0.42) F10F2PLAUPLATKDM4E
SCHEMBL7255333 0.86 F10 (0.40) F10F2PLAUPLATITGB3
SCHEMBL7251419 0.86 MEN1 (0.42) F10F2PLAUPLATITGB3
SCHEMBL7037933 0.86 ITGB3 (0.46) F10F2PLAUPLATITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed
WO-1999052879-A1 ACYLRESORCINOL DERIVATIVES AS SELECTIVE VITRONECTIN RECEPTOR INHIBITORS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR F10 2695/4885F2 4014/4885PLAU 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.