SCHEMBL7030499

SCHEMBL7030499

N=C(N)NCCOc1ccc(C(=O)NC[C@H](NC(=O)Nc2ccccc2-c2ccccc2)C(=O)O)c(O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 4/20 0.38
PLG P00747 1/20 0.38
PROC P04070 1/20 0.38
KLK1 P06870 1/20 0.38
PRSS1 P07477 1/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
POLB P06746 1/20 0.37
ITGB3 P05106 4/20 0.36
ITGAV P06756 2/20 0.36
F2 P00734 1/20 0.35
PLAU P00749 1/20 0.35
PLAT P00750 1/20 0.35
CA4 P22748 1/20 0.35
ALDH1A1 P00352 4/20 0.35
L3MBTL1 Q9Y468 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7035239 0.90 F10 (0.38) F10CA1CA2CA9KMT2A
SCHEMBL7032586 0.90 PYGL (0.41) F10CA1CA2CA9KMT2A
SCHEMBL7038269 0.90 PYGL (0.41) F10KMT2AMEN1POLBITGB3
SCHEMBL7036653 0.89 MEN1 (0.46) F10CA12CA1CA2CA9
SCHEMBL7036018 0.89 F10 (0.42) F10KMT2AMEN1POLBITGB3
SCHEMBL7034753 0.89 ALDH1A1 (0.43) KMT2AMEN1POLBALDH1A1NPSR1
SCHEMBL7037756 0.86 KDM4E (0.38) CA12CA1CA2CA9KMT2A
SCHEMBL7039300 0.85 F10 (0.46) F10PLGPROCKLK1PRSS1
SCHEMBL7039028 0.85 ITGB3 (0.41) F10KMT2AMEN1POLBITGB3
SCHEMBL7037069 0.85 ITGB3 (0.43) F10PLGPROCKLK1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR F10 2695/4885PLG 3106/4885PROC 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.