Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.66 |
| ▸ | CTSG | P08311 | 2/20 | 0.51 |
| ▸ | CMA1 | P23946 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | VDR | P11473 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681428 | 0.88 | PTGDR2 (0.71) | PTGDR2L3MBTL1DRD2TBXA2R | |
| SCHEMBL9683001 | 0.87 | CTSG (0.66) | PTGDR2CTSGCMA1LMNAVDR | |
| SCHEMBL7035111 | 0.82 | PTGDR2 (0.69) | PTGDR2CTSGCMA1SMN1; SMN2AR | |
| SCHEMBL14577952 | 0.81 | PTGDR2 (0.67) | PTGDR2CTSGCMA1LMNASMN1; SMN2 | |
| SCHEMBL7030671 | 0.81 | PTGDR2 (0.67) | PTGDR2CTSGCMA1ARKMT2A | |
| SCHEMBL5109787 | 0.80 | PTGDR2 (1.00) | PTGDR2MEN1KMT2A | |
| SCHEMBL5266755 | 0.79 | PTGDR2 (0.64) | PTGDR2CTSGCMA1ARKMT2A | |
| SCHEMBL9682402 | 0.77 | CYP2D6 (0.45) | PTGDR2LMNASMN1; SMN2MEN1CYP2D6 | |
| SCHEMBL9581575 | 0.77 | TBXA2R (0.58) | PTGDR2NPSR1DRD2TBXA2R | |
| SCHEMBL5109861 | 0.77 | PTGDR2 (1.00) | PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |