Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971003 | 0.84 | TDP1 (0.38) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| Oxalic Acid SCHEMBL15154934 | 0.78 | LMNA (0.42) | NR3C2HTR7 | |
| SCHEMBL22043585 | 0.73 | FADS1 (0.40) | HTR7ALDH1A1KDM4E | |
| SCHEMBL4620798 | 0.73 | SLC5A2 (0.35) | — | |
| SCHEMBL28758463 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1CA12CA1 | |
| SCHEMBL4837968 | 0.72 | PRCP (0.46) | TDP1 | |
| SCHEMBL4620026 | 0.72 | ALDH1A1 (0.62) | NR3C2BCL2L1BADHTR7ALDH1A1 | |
| SCHEMBL17332097 | 0.67 | BCL2L1 (0.81) | BCL2L1BADALDH1A1KDM4ECA12 | |
| SCHEMBL24503134 | 0.66 | SRD5A2 (0.49) | BCL2L1BADALDH1A1TDP1HIF1A | |
| SCHEMBL22776035 | 0.66 | KDM1A (0.60) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338051-C | Process for the preparation of citalopram | LUNDHECK AS H (DK) | 2007-09-19 | — | — | CN | disclosed |
| EP-1032566-B9 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2003-10-22 | — | — | EP | disclosed |
| EP-1032566-B1 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2003-02-12 | — | — | EP | disclosed |
| US-6291689-B1 | CYCLIZING 4-CYANO-2-HYDROXYMETHYLPHENYL)(4-FLUOROPHENYL)METHANOL TO FORM 1-(4-FLUOROPHENYL)-1,3-DIHYDROISOBENZOFURAN-5-CARBONITRILE; ALKYLATING TO FORM CITALOPRAM | H. LUNDBECK A/S (DK) | 2001-09-18 | — | — | US | disclosed |
| CN-1286688-A | Process for the preparation of citalopram | LUNDHECK AS H (DK) | 2001-03-07 | — | — | CN | disclosed |