Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021488 | 0.82 | ADRB2 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL7024493 | 0.81 | MEN1 (0.49) | MEN1KMT2APKMMTNR1AMTNR1B | |
| SCHEMBL2936654 | 0.77 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL15142696 | 0.77 | HRH1 (0.48) | MEN1KMT2APKMMTNR1AMTNR1B | |
| SCHEMBL9570663 | 0.76 | L3MBTL1 (0.42) | ALDH1A1HRH1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3470702 | 0.75 | SMN1; SMN2 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19384152 | 0.75 | KDM4E (0.49) | ALDH1A1HRH1SMN1; SMN2KDM4E | |
| SCHEMBL19743651 | 0.75 | MTNR1A (0.51) | MEN1KMT2APKMMTNR1AMTNR1B | |
| SCHEMBL25433158 | 0.74 | KDM4E (0.62) | MEN1KMT2APKMMTNR1AMTNR1B | |
| SCHEMBL7072684 | 0.74 | MTNR1A (0.77) | KMT2AMTNR1AMTNR1BSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |