Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445274 | 0.92 | MAPT (0.48) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9834537 | 0.90 | CYP1A2 (0.46) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10634246 | 0.87 | CYP1A2 (0.51) | L3MBTL1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL7781498 | 0.85 | L3MBTL1 (0.47) | L3MBTL1CYP1A2CYP2C9TSHRMAPT | |
| SCHEMBL17008035 | 0.81 | KDM4E (0.48) | L3MBTL1TSHRMAPTNPSR1HPGD | |
| SCHEMBL7197450 | 0.81 | L3MBTL1 (0.55) | L3MBTL1CYP1A2CYP2C9TSHRMAPT | |
| SCHEMBL31391959 | 0.81 | ALDH1A1 (0.41) | L3MBTL1CYP1A2MAPTNPSR1HPGD | |
| SCHEMBL4388500 | 0.80 | HRH1 (0.64) | L3MBTL1CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL3150720 | 0.78 | HTR1A (0.61) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7200892 | 0.77 | ALDH1A1 (0.49) | L3MBTL1CYP1A2CYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |