Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477072 | 0.74 | FAAH (0.56) | FAAHGPR119KDM4EPKM | |
| SCHEMBL15085741 | 0.74 | GPR119 (0.59) | FAAHGPR119KDM4EPKM | |
| SCHEMBL3476578 | 0.73 | FAAH (0.55) | FAAHGPR119GLS | |
| SCHEMBL6794692 | 0.73 | FAAH (0.56) | FAAHGPR119KDM4EPKM | |
| SCHEMBL20077080 | 0.73 | FAAH (0.58) | FAAHGPR119KDM4EPKM | |
| SCHEMBL13999420 | 0.73 | FAAH (0.58) | FAAHGPR119KDM4EPKM | |
| SCHEMBL544238 | 0.73 | FAAH (0.58) | FAAHGPR119KDM4EPKM | |
| SCHEMBL2539468 | 0.72 | GPR119 (0.67) | FAAHGPR119 | |
| SCHEMBL3478015 | 0.72 | FAAH (0.57) | FAAHGPR119KDM4EPKM | |
| SCHEMBL459905 | 0.71 | MAPT (0.51) | GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | FAAH 604/4885GPR119 1119/4885GLS 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.