Sugi Predict

Sugi Predict / Compounds / SCHEMBL703276

SCHEMBL703276

SCHEMBL703276

COc1ccc(N=C=O)c(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.71
▸ CYP3A4 P08684 3/20 0.71
▸ HPGD P15428 2/20 0.71
▸ TDP1 Q9NUW8 1/20 0.71
▸ CYP1B1 Q16678 4/20 0.50
▸ CA12 O43570 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ CA7 P43166 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ CA14 Q9ULX7 1/20 0.50
▸ CYP1A1 P04798 3/20 0.44
▸ CYP1A2 P05177 3/20 0.44
▸ MAPT P10636 5/20 0.43
▸ KMT2A Q03164 5/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ PKM P14618 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29541267 1.00 ALDH1A1 (0.71) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL8942826 0.92 ALDH1A1 (0.61) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL7529762 0.92 ALDH1A1 (0.61) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL11194657 0.91 ALDH1A1 (0.69) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL29538723 0.85 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL374346 0.85 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL10316751 0.85 ALDH1A1 (0.55) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL14992 0.83 CYP3A4 (1.00) ALDH1A1CYP3A4HPGDTDP1CA12
SCHEMBL29825539 0.83 CA12 (0.52) ALDH1A1CYP3A4HPGDTDP1CYP1B1
SCHEMBL222435 0.83 CA12 (0.52) ALDH1A1CYP3A4HPGDTDP1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 — — EP claimed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 — — EP disclosed
US-20260078126-A1 BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2026-03-19 — — US disclosed
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 ZHOU YUHANG (US) 2025-09-11 — — US disclosed
US-12398145-B2 Bicyclic urea kinase inhibitors and uses thereof THE BROAD INSTITUTE, INC. (US) 2025-08-26 — — US disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 — — EP disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 — — WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 — — EP disclosed
US-12121521-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2024-10-22 — — US disclosed
US-20240245695-A1 USES OF PYRIMIDOPYRIMIDINONES AS SIK INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2024-07-25 — — US disclosed
US-4775757-A CARDIOTONIC AND RENAL VASODILATING AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-10-04 — — US disclosed
EP-0245637-A1 4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine derivatives and analogs having antihypertensive activity WARNER-LAMBERT COMPANY (US) 1987-11-19 — — EP disclosed
EP-0073146-B1 METHOD AND MATERIAL FOR THE FORMATION OF SILVER HALIDE COLOR PHOTOGRAPHIC IMAGE KONICA CORPORATION (JP) 1986-06-11 — — EP disclosed
US-4444872-A CYAN PHENOLIC COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-04-24 — — US disclosed
EP-0073146-A1 Method and material for the formation of silver halide color photographic image KONICA CORPORATION (JP) 1983-03-02 — — EP disclosed
US-4098788-A Process for preparing quinazolines BRISTOL-MYERS COMPANY (US) 1978-07-04 — — US disclosed
US-4032638-A Heterocyclic ureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-28 — — US disclosed
US-3975433-A ANTIDEPRESSANT, PARASITICIDE THE DOW CHEMICAL COMPANY (US) 1976-08-17 — — US disclosed
US-3973946-A Substituted-3-phenyl ureas E. I. DUPONT DE NEMOURS & COMPANY (US) 1976-08-10 — — US disclosed
US-3969532-A 1-Aryl-3-(2-hydroxyethyl) thioureas for treating depression THE DOW CHEMICAL COMPANY (US) 1976-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12121521-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis SOST, CSF1R, SIK2 ALDH1A1 4666/4885CYP3A4 4879/4885HPGD 3358/4885
US-20260078126-A1 BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF SIK2, SBK3, SIK3 ALDH1A1 4254/4885CYP3A4 4126/4885HPGD 3794/4885
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 PF4, F12, F2 ALDH1A1 4728/4885CYP3A4 757/4885HPGD 2280/4885
US-12398145-B2 Bicyclic urea kinase inhibitors and uses thereof SIK1, SIK2, SIK3 ALDH1A1 3729/4885CYP3A4 4312/4885HPGD 2337/4885
US-20240245695-A1 USES OF PYRIMIDOPYRIMIDINONES AS SIK INHIBITORS SIK2, SIK1, SIK3 ALDH1A1 1744/4885CYP3A4 3080/4885HPGD 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.