Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | PNMT | P11086 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.45 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668896 | 1.00 | CYP3A4 (0.68) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL4706452 | 1.00 | CYP3A4 (0.68) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL9985739 | 1.00 | CYP3A4 (0.68) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| Hydrochloric Acid SCHEMBL27164837 | 0.98 | LMNA (0.69) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| Hydrochloric Acid SCHEMBL1847345 | 0.98 | LMNA (0.69) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| Hydrochloric Acid SCHEMBL30063553 | 0.98 | LMNA (0.69) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| Hydrochloric Acid SCHEMBL19205652 | 0.98 | LMNA (0.69) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| Hydrochloric Acid SCHEMBL29668976 | 0.98 | LMNA (0.69) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL11084981 | 0.86 | CYP3A4 (0.57) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL11413072 | 0.82 | CYP2D6 (0.53) | CYP3A4CYP1A2CYP2D6NFKB1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118726998-A | Preparation method for preparing benzyl carboxylic acid compound from benzylamine and carbon dioxide | 哈尔滨工业大学（深圳） | 2024-10-01 | — | — | CN | claimed |
| CN-115245483-A | Immune cell preparation and preparation method thereof | 昆山美卡生物医药科技有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-114230781-A | Preparation method of low molecular weight polycarbonate polyether polyol with autocatalysis effect | 河北工业大学 | 2022-03-25 | — | — | CN | claimed |
| CN-108250151-B | Preparation method of ambrisentan | 济南周行医药科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-112375042-A | Trimethoxy styryl six-membered ring and pyrazolopyrimidine compound, preparation and application thereof | 安徽医科大学 | 2021-02-19 | — | — | CN | claimed |
| CN-110357901-B | Aromatic ring vinyl thieno pyrimidine compound, preparation method and application of compound | 安徽医科大学 | 2020-06-23 | — | — | CN | claimed |
| CN-110615801-A | Preparation method and application of triazine compound with polyvinyl chloride light stabilization effect | 河南龙湖生物技术有限公司 | 2019-12-27 | — | — | CN | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| CN-108250151-A | A kind of preparation method of ambrisentan | 济南周行医药科技有限公司 | 2018-07-06 | — | — | CN | claimed |
| WO-2014001075-A1 | PROCESS FOR RACEMIZING OPTICALLY ACTIVE ARYLALKYLAMINES | BASF SE (DE) | 2014-01-03 | — | — | WO | claimed |
| US-20130345475-A1 | PROCESS FOR THE RACEMIZATION OF OPTICALLY ACTIVE ARYLALKYLAMINES | BASF SE (DE) | 2013-12-26 | — | — | US | claimed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | claimed |
| CN-101410366-A | Substituted bicyclic ring derivatives and uses thereof | ASAHI KASEI PHARMA CORP (JP) | 2009-04-15 | — | — | CN | claimed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | claimed |
| EP-2006271-A2 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2008-12-24 | — | — | EP | claimed |
| EP-1773768-A4 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2008-08-06 | — | — | EP | claimed |
| EP-1773768-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| CN-1646502-A | Triazole derivatives as tachykinin receptor antagonists | LILLY CO ELI (US) | 2005-07-27 | — | — | CN | claimed |
| US-4209638-A | RESOLUTION OF ENANTIOMORPHS | THE BOOTS COMPANY LIMITED (GB) | 1980-06-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | LTB4R2, LTC4S, LTB4R | CYP3A4 1212/4885CYP1A2 612/4885CYP2D6 603/4885 |
| US-20130345475-A1 | PROCESS FOR THE RACEMIZATION OF OPTICALLY ACTIVE ARYLALKYLAMINES | HRH1, HNMT, HRH3 | CYP3A4 24/4885CYP1A2 18/4885CYP2D6 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.