Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | DDT | P30046 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499925 | 0.80 | CRBN (0.45) | RXRARXRBKDM4EALDH1A1NPC1 | |
| SCHEMBL6678037 | 0.77 | BRD4 (0.30) | — | |
| SCHEMBL6658548 | 0.76 | FAAH (0.33) | HPGD | |
| Fluoride SCHEMBL21332075 | 0.75 | KMO (0.83) | KMOKEAP1RXRARXRBCD74 | |
| SCHEMBL10750315 | 0.75 | KMO (0.46) | KMOKEAP1RXRARXRBCD74 | |
| SCHEMBL29904709 | 0.73 | KMO (0.86) | KMOKEAP1RXRARXRBCD74 | |
| SCHEMBL30725957 | 0.73 | KMO (0.86) | KMOKEAP1RXRARXRBCD74 | |
| SCHEMBL71238 | 0.73 | KMO (0.86) | KMOKEAP1RXRARXRBCD74 | |
| Water SCHEMBL10348973 | 0.71 | KMO (0.83) | KMOKEAP1RXRARXRBCD74 | |
| Hydrochloric Acid SCHEMBL21173951 | 0.71 | KMO (0.83) | KMOKEAP1RXRARXRBCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020152200-A1 | PROCESS FOR PREPARATION OF HETEROARYLKETONES | BASF SE (DE) | 2020-07-30 | — | — | WO | disclosed |
| US-8124810-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8049017-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | RHEINHEIMER JOACHIM | 2011-06-23 | — | — | US | disclosed |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7663001-B2 | Preparation of isoxazolin-3-ylacylbenzene | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-16 | — | — | US | disclosed |
| US-7309802-B2 | Preparation of isoxazolin-3-ylacylbenzene | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-18 | — | — | US | disclosed |
| US-20070161800-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | BASF SE (DE) | 2007-07-12 | — | — | US | disclosed |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | BASF SE (DE) | 2003-11-20 | — | — | US | disclosed |
| US-6541642-B1 | Reaction of crotonaldehyde with hydroxylamine, followed by a reaction of the produced oxime, while changing to nitrile oxide, with ethylene to form (E)-3-(1-propenyul)-2-iosxazoline | NIPPON SODA CO., LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| EP-1174429-A1 | PROCESS FOR THE PREPARATION OF (E)-3-(1-PROPENYL)ISOXAZOLINE | NIPPON SODA CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161800-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | CBR3, UQCRB, CYP4X1 | KMO 525/4885KEAP1 2177/4885RXRA 423/4885 |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | KMO 556/4885KEAP1 2189/4885RXRA 445/4885 |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | KMO 556/4885KEAP1 2189/4885RXRA 445/4885 |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | UQCRB, CYP1B1, CYP2F1 | KMO 647/4885KEAP1 2792/4885RXRA 387/4885 |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | KMO 704/4885KEAP1 3015/4885RXRA 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.