Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033915 | 0.81 | HTR2C (0.34) | HTR2CUSP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7036280 | 0.81 | HTR2C (0.35) | RORCHTR2CUSP2ALDH1A1TSHR | |
| Oxalic Acid SCHEMBL6485167 | 0.74 | KDM4E (0.33) | HTR2CHSD17B10HTR2A | |
| Oxalic Acid SCHEMBL6496099 | 0.74 | HTR2C (0.42) | HTR2CALDH1A1HSD17B10HTR2A | |
| SCHEMBL7033172 | 0.72 | HTR6 (0.35) | RORCHTR2CUSP2ALDH1A1TSHR | |
| SCHEMBL6502851 | 0.72 | HTR2A (0.34) | HTR2CHSD17B10HTR2A | |
| SCHEMBL6501128 | 0.72 | HTR2C (0.47) | HTR2CHSD17B10HTR2A | |
| SCHEMBL7037088 | 0.71 | HTR6 (0.34) | HTR2C | |
| SCHEMBL7036278 | 0.70 | HTR6 (0.35) | HTR2CDRD1HSD17B10HTR2A | |
| SCHEMBL7031087 | 0.69 | HTR2C (0.35) | RORCHTR2CUSP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173440-B1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | claimed |