SCHEMBL7034616

SCHEMBL7034616

C=Cc1ccc(C(C=C)OS(=O)(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7034612 0.86 TDP1 (0.41) TDP1ALDH1A1TSHR
SCHEMBL778797 0.82 SRC (0.40) TDP1ALDH1A1TSHR
SCHEMBL17183032 0.72 TDP1 (0.55) TDP1ALDH1A1TSHRMCL1
SCHEMBL6872771 0.71 KMT2A (0.40) TDP1ALDH1A1
SCHEMBL11876836 0.69 TDP1 (0.52) TDP1ALDH1A1TSHR
SCHEMBL237458 0.68 TDP1 (0.55) TDP1ALDH1A1TSHR
Vinylsulfonic Acid SCHEMBL28173702 0.68 TDP1 (0.74) TDP1ALDH1A1TSHRMCL1
SCHEMBL629069 0.68
SCHEMBL778796 0.67 MAPT (0.37) TDP1ALDH1A1TSHR
SCHEMBL630115 0.67 CES2 (0.36) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787621-B2 USING DIARYLETHENE MONOMERS FOR MAKING PHOTOCHROMIC POLYMERIZABLE THIN FILM KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2004-09-07 US disclosed
US-20030130456-A1 Vinyl group-containing diarylethene and polymer thereof having excellent optical properties KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2003-07-10 US disclosed