SCHEMBL237458

SCHEMBL237458

C=Cc1ccc(OS(=O)(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
CISD1 Q9NZ45 1/20 0.47
ALDH1A1 P00352 5/20 0.46
STS P08842 2/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
PTGS2 P35354 1/20 0.40
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
TSHR P16473 2/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL15671145 0.85 ABL1 (0.45) TDP1CISD1ALDH1A1STSMAPT
SCHEMBL375417 0.83 ALDH1A1 (0.50) TDP1ALDH1A1STSPTGS2CA2
SCHEMBL15649102 0.83 CISD1 (0.65) TDP1CISD1ALDH1A1STSGLA
SCHEMBL28148408 0.82 TDP1 (0.50) TDP1CISD1ALDH1A1STSPTGS2
SCHEMBL7910581 0.82 GLA (0.53) TDP1CISD1STSGLAGAA
SCHEMBL3042573 0.81 STS (0.64) CISD1ALDH1A1STSGLAGAA
SCHEMBL28385519 0.81 ALDH1A1 (0.48) TDP1ALDH1A1STSPTGS2CA2
Ammonia Solution, Strong SCHEMBL2908474 0.79 GLA (0.52) TDP1CISD1STSGLAGAA
SCHEMBL1005410 0.79 ALDH1A1 (0.46) TDP1ALDH1A1STSPTGS2CA2
SCHEMBL941732 0.79 ALDH1A1 (0.46) TDP1ALDH1A1STSGAACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1093 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20250262668-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2025-08-21 US claimed
US-12358052-B2 Three-dimensional printing PERIDOT PRINT LLC (US) 2025-07-15 US claimed
US-12337382-B2 Three-dimensional printing PERIDOT PRINT LLC (US) 2025-06-24 US claimed
US-12251873-B2 Three-dimensional printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2025-03-18 US claimed
US-12186805-B2 Three-dimensional printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2025-01-07 US claimed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP claimed
EP-4424365-A2 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2024-09-04 EP claimed
EP-4017281-B1 PET FOOD COMPOSITIONS HILLS PET NUTRITION INC (US) 2024-08-28 EP claimed
CN-118435054-A Compositions and methods for diagnosing and treating chronic kidney disease 雀巢产品有限公司 2024-08-02 CN claimed
WO-2001093911-A2 MACROMOLECULAR DRUG COMPLEXES AND COMPOSITIONS CONTAINING THE SAME THE BOARD OF TRUSTESS OF THE UNIVERSITY OF ILLINOIS (US) 2001-12-13 WO claimed
US-20010048941-A1 Method for treating amyloidosis QUEEN'S UNIVERSITY OF KINGSTON 2001-12-06 US claimed
US-6281180-B1 Automatic dishwashing compositions containing water soluble cationic or amphoteric polymers LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. 2001-08-28 US claimed
EP-1060750-A2 Method for treating amyloidosis Queen's University at Kingston (CA) 2000-12-20 EP claimed
US-6063370-A DRUG, POLYMER COMPLEX THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2000-05-16 US claimed
WO-1997037680-A1 MACROMOLECULAR COMPLEXES FOR DRUG DELIVERY THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1997-10-16 WO claimed
US-5643562-A ANTIDEPOSIT AGENTS FOR PROTEINS FOR MEDICAL DIAGNOSIS OF DISEASES QUEEN'S UNIVERSITY OF KINGSTON (CA) 1997-07-01 US claimed
US-5589324-A INTERPENETRATING POLYMER NETWORKS INTERNATIONAL PAPER COMPANY (US) 1996-12-31 US claimed
EP-0691844-A1 METHOD FOR TREATING AMYLOIDOSIS QUEEN'S UNIVERSITY AT KINGSTON (CA) 1996-01-17 EP claimed
WO-1994022437-A2 METHOD FOR TREATING AMYLOIDOSIS QUEEN'S UNIVERSITY AT KINGSTON (CA) 1994-10-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 TDP1 3493/4885CISD1 3448/4885ALDH1A1 822/4885
US-20010048941-A1 Method for treating amyloidosis TTR, APOB, NEFM TDP1 4164/4885CISD1 3667/4885ALDH1A1 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.