SCHEMBL7034612

SCHEMBL7034612

C=Cc1ccc(C(C=C)OS(=O)(=O)OC(C=C)c2ccc(C=C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HDAC8 Q9BY41 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7034616 0.86 TDP1 (0.47) TDP1ALDH1A1TSHR
SCHEMBL778796 0.81 MAPT (0.37) TDP1ALDH1A1TSHR
SCHEMBL17183032 0.67 TDP1 (0.55) TDP1ALDH1A1HDAC8TSHR
SCHEMBL1169874 0.67 KDM4E (0.39) TDP1ALDH1A1TSHR
SCHEMBL17359706 0.67 CA1 (0.39) TDP1
SCHEMBL778797 0.67 SRC (0.40) TDP1ALDH1A1TSHR
SCHEMBL7763428 0.66 CHRNB2 (0.40) ALDH1A1TSHR
SCHEMBL375417 0.66 ALDH1A1 (0.50) TDP1ALDH1A1HDAC8TSHR
SCHEMBL6946790 0.65 ALDH1A1 (0.65) TDP1ALDH1A1HDAC8TSHR
SCHEMBL12891204 0.64 TDP1 (0.47) TDP1ALDH1A1HDAC8TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787621-B2 USING DIARYLETHENE MONOMERS FOR MAKING PHOTOCHROMIC POLYMERIZABLE THIN FILM KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2004-09-07 US disclosed
US-20030130456-A1 Vinyl group-containing diarylethene and polymer thereof having excellent optical properties KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2003-07-10 US disclosed