Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27428297 | 0.77 | CES2 (0.35) | CES2CES1KEAP1ALOX5RAB9A | |
| SCHEMBL29003427 | 0.75 | ALOX5 (0.42) | CES2CES1KEAP1ALOX5RAB9A | |
| SCHEMBL5009527 | 0.75 | CES2 (0.39) | CES2CES1KEAP1ALOX5RAB9A | |
| SCHEMBL5742124 | 0.74 | HSD17B2 (0.40) | CES2CES1KEAP1ALOX5RAB9A | |
| SCHEMBL28219608 | 0.74 | CNR2 (0.36) | CES2CES1KEAP1ALOX5TSHR | |
| SCHEMBL5836645 | 0.73 | ALOX5 (0.39) | CES2CES1KEAP1ALOX5RAB9A | |
| SCHEMBL778797 | 0.73 | SRC (0.40) | KMT2AALDH1A1LMNAMEN1TSHR | |
| SCHEMBL628049 | 0.71 | RAB9A (0.37) | CES2CES1KEAP1ALOX5RAB9A | |
| SCHEMBL22733837 | 0.70 | MEN1 (0.33) | CES2CES1KEAP1KMT2AALDH1A1 | |
| SCHEMBL629069 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1693370-B1 | SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| CN-100469775-C | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2009-03-18 | — | — | CN | claimed |
| US-7371873-B2 | Sulfoxyalkylthiophene and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-05-13 | — | — | US | claimed |
| US-20070260071-A1 | Sulfoxyalkylthiophene and Process for Producing the Same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-11-08 | — | — | US | claimed |
| EP-1693370-B1 | SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2012-02-22 | — | — | EP | disclosed |
| EP-1693370-B1 | SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2012-02-22 | — | — | EP | disclosed |
| CN-100469775-C | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| CN-100469775-C | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| CN-100469775-C | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| US-7371873-B2 | Sulfoxyalkylthiophene and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371873-B2 | Sulfoxyalkylthiophene and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20070260071-A1 | Sulfoxyalkylthiophene and Process for Producing the Same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-11-08 | — | — | US | disclosed |
| US-20070260071-A1 | Sulfoxyalkylthiophene and Process for Producing the Same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-11-08 | — | — | US | disclosed |
| EP-1693370-A4 | SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2007-09-05 | — | — | EP | disclosed |
| CN-1890233-A | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1890233-A | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1890233-A | Sulfoxyalkylthiophene compound and process for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2007-01-03 | — | — | CN | disclosed |
| EP-1693370-A1 | SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056545-A1 | SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260071-A1 | Sulfoxyalkylthiophene and Process for Producing the Same | TST, SULT1A1, MPST | CES2 1776/4885CES1 4071/4885KEAP1 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.