SCHEMBL7034909

SCHEMBL7034909

CCn1cnc2nc3ccccc3nc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
ALDH1A1 P00352 7/20 0.42
MAPT P10636 6/20 0.42
HSD17B10 Q99714 5/20 0.42
TSHR P16473 5/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
USP2 O75604 3/20 0.42
CASP1 P29466 3/20 0.42
CASP7 P55210 3/20 0.42
NPC1 O15118 1/20 0.42
HCRTR1 O43613 1/20 0.42
TP53 P04637 1/20 0.42
CDK1 P06493 1/20 0.40
CCNB1 P14635 1/20 0.40
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40
TDP1 Q9NUW8 4/20 0.40
MAPK1 P28482 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7111137 0.82 ALDH1A1 (0.48) KDM4EALDH1A1MAPTHSD17B10TSHR
SCHEMBL7034506 0.81 DPP4 (0.42) KDM4EALDH1A1MAPTHSD17B10L3MBTL1
SCHEMBL7094273 0.79 KDM4E (0.52) KDM4EALDH1A1MAPTHSD17B10TSHR
SCHEMBL7034501 0.78 HPGD (0.55) KDM4EALDH1A1MAPTHSD17B10USP2
SCHEMBL7092051 0.76 GRM5 (0.40) KDM4EALDH1A1MAPTHSD17B10TSHR
SCHEMBL975642 0.75 ALDH1A1 (0.39) KDM4EALDH1A1MAPTHSD17B10TSHR
SCHEMBL8970101 0.70 MEN1 (0.51) TP53CDK1CCNB1CCNE1CDK2
SCHEMBL226221 0.69 TDP1 (0.70) ALDH1A1L3MBTL1TDP1MAPK1MEN1
SCHEMBL7033144 0.69 HTT (0.52) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL9283976 0.68 KDM4E (0.38) KDM4EALDH1A1MAPTHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1291714-A1 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
EP-1288709-A1 A thermally bleachable dye for a color photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-05 EP disclosed
US-RE37962-E1 Photopolymerizable composition containing a sensitizing dye and a titanocene compound FUJI PHOTO FILM CO., LTD. (JP) 2003-01-07 US disclosed
US-6492076-B1 UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE EASTMAN KODAK COMPANY 2002-12-10 US disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
US-5700849-A SENSITIVE TO VISIBLE LIGHT, LASER LIGHT SOURCE FUJI PHOTO FILM CO., LTD. (JP) 1997-12-23 US disclosed
EP-0520364-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1997-09-17 EP disclosed
US-5424442-A Eliminates the need to use organic solvents and other solubilizing additives FUJI PHOTO FILM CO., LTD. (JP) 1995-06-13 US disclosed
US-5385807-A Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1995-01-31 US disclosed
US-5250692-A Water-soluble methine compounds useful in photographic silver halide emulsions FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0520364-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1992-12-30 EP disclosed
EP-0452965-A1 Water-soluble methine compound and photographic silver halide emulsion containing the same FUJI PHOTO FILM CO., LTD. (JP) 1991-10-23 EP disclosed
US-4273862-A ANIONIC CYANINE DYE, HYDROQUINONE FRBRLOPRT MITSUBISHI PAPER MILLS, LTD. (JP) 1981-06-16 US disclosed
US-4259439-A DIMETHINECYANINE DYE SENSITIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1981-03-31 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed