SCHEMBL7034501

SCHEMBL7034501

C=CCn1cnc2nc3ccccc3nc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.55
ALDH1A1 P00352 8/20 0.55
HSD17B10 Q99714 5/20 0.55
KDM4E B2RXH2 8/20 0.50
GAA P10253 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
GLA P06280 2/20 0.49
TP53 P04637 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
HIF1A Q16665 2/20 0.46
MAPT P10636 3/20 0.44
KMT2A Q03164 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PDE4B Q07343 1/20 0.41
PDE4D Q08499 1/20 0.41
USP2 O75604 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7033155 0.83 HIF1A (0.44) HPGDALDH1A1HSD17B10KDM4EGAA
SCHEMBL9843438 0.81 HIF1A (0.37) HPGDALDH1A1HSD17B10KDM4EGAA
SCHEMBL7034909 0.78 KDM4E (0.42) HPGDALDH1A1HSD17B10KDM4EGAA
SCHEMBL9680210 0.77 ALDH1A1 (0.42) HPGDALDH1A1HSD17B10KDM4EGAA
SCHEMBL8876041 0.73 KMT2A (0.48) HPGDALDH1A1HSD17B10KDM4EGAA
SCHEMBL326813 0.73 TDP1 (0.63) SMN1; SMN2NPSR1LMNA
SCHEMBL7094273 0.72 KDM4E (0.52) HPGDALDH1A1HSD17B10KDM4EGAA
SCHEMBL7111137 0.72 ALDH1A1 (0.48) HPGDALDH1A1HSD17B10KDM4EGAA
Bromide SCHEMBL11005339 0.71 TDP1 (0.61) SMN1; SMN2NPSR1LMNA
SCHEMBL11311146 0.70 ADORA2B (0.41) HPGDALDH1A1HSD17B10KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1291714-A1 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
EP-1288709-A1 A thermally bleachable dye for a color photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-05 EP disclosed
US-6492076-B1 UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE EASTMAN KODAK COMPANY 2002-12-10 US disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
US-5166046-A Light sensitive element with sensitizers KONICA CORPORATION (JP) 1992-11-24 US disclosed
EP-0439356-A1 Spectrally sensitized silver halide photographic material KONICA CORPORATION (JP) 1991-07-31 EP disclosed
US-4273862-A ANIONIC CYANINE DYE, HYDROQUINONE FRBRLOPRT MITSUBISHI PAPER MILLS, LTD. (JP) 1981-06-16 US disclosed
US-4259439-A DIMETHINECYANINE DYE SENSITIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1981-03-31 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed