SCHEMBL7111137

SCHEMBL7111137

CCCCCn1cnc2nc3ccccc3nc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
HPGD P15428 6/20 0.48
KDM4E B2RXH2 5/20 0.48
GAA P10253 3/20 0.48
HSD17B10 Q99714 3/20 0.48
GLA P06280 3/20 0.48
CASP1 P29466 2/20 0.48
CASP7 P55210 2/20 0.48
ALOX15 P16050 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 1/20 0.46
CRHBP P24387 1/20 0.46
CYP2C19 P33261 1/20 0.46
CRHR2 Q13324 1/20 0.46
POLB P06746 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524592 0.84 TLR8 (0.40) ALDH1A1HPGDKDM4EGAAHSD17B10
SCHEMBL7034909 0.82 KDM4E (0.42) ALDH1A1HPGDKDM4EGAAHSD17B10
SCHEMBL7092147 0.79 TSHR (0.41) ALDH1A1HPGDKDM4EGAAHSD17B10
SCHEMBL7094273 0.79 KDM4E (0.52) ALDH1A1HPGDKDM4EGAAHSD17B10
SCHEMBL13749571 0.75 MEN1 (0.46) ALOX15TSHRKMT2AMEN1MAPT
SCHEMBL6112450 0.75 MEN1 (0.48) ALDH1A1HPGDKDM4EGAAHSD17B10
SCHEMBL327149 0.74 TDP1 (0.70) ALOX15L3MBTL1TSHRNPSR1KMT2A
SCHEMBL13527216 0.74 MEN1 (0.45) KMT2AMEN1TLR8SLC9A1
SCHEMBL7092051 0.73 GRM5 (0.40) ALDH1A1HPGDKDM4EGAAHSD17B10
SCHEMBL16097150 0.73 TDP1 (0.68) ALOX15L3MBTL1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1291714-A1 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
EP-1288709-A1 A thermally bleachable dye for a color photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-05 EP disclosed
US-6492076-B1 UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE EASTMAN KODAK COMPANY 2002-12-10 US disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed