SCHEMBL7035563

SCHEMBL7035563

CC(C)n1nc(C#CC2(O)CCSCC2)ccc1=O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FLT4 P35916 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7032865 0.88 FLT4 (0.41) FLT4
SCHEMBL7039195 0.87 FLT4 (0.40) FLT4
SCHEMBL7038833 0.85 HPGD (0.34) FLT4
SCHEMBL7042064 0.84 FLT4 (0.32) FLT4
SCHEMBL7036150 0.74 HRH3 (0.32)
SCHEMBL7038464 0.71 BMPR1B (0.30)
SCHEMBL6134347 0.69 BMPR1B (0.30)
SCHEMBL7036863 0.69 FLT4 (0.37) FLT4
SCHEMBL6133575 0.65 RET (0.44)
SCHEMBL7037693 0.65 CCNB2 (0.35) FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003004494-A1 PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-01-16 WO disclosed