Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039195 | 0.96 | FLT4 (0.40) | FLT4PAX8NPC1RAB9APOLB | |
| SCHEMBL7035563 | 0.88 | FLT4 (0.33) | FLT4 | |
| SCHEMBL7038833 | 0.88 | HPGD (0.34) | FLT4HPGDSMN1; SMN2 | |
| SCHEMBL7042064 | 0.87 | FLT4 (0.32) | FLT4HRH3 | |
| SCHEMBL7036150 | 0.79 | HRH3 (0.32) | HRH3 | |
| SCHEMBL7038464 | 0.74 | BMPR1B (0.30) | POLB | |
| SCHEMBL6134347 | 0.72 | BMPR1B (0.30) | — | |
| SCHEMBL5147966 | 0.69 | ADORA2B (0.36) | FLT4CDK1CCNB1TNIK | |
| SCHEMBL6133575 | 0.68 | RET (0.44) | — | |
| SCHEMBL7037693 | 0.68 | CCNB2 (0.35) | FLT4MAP3K14CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |