Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032865 | 0.88 | FLT4 (0.41) | HPGDSMN1; SMN2FLT4 | |
| SCHEMBL7039195 | 0.87 | FLT4 (0.40) | HPGDSMN1; SMN2FLT4 | |
| SCHEMBL7035563 | 0.85 | FLT4 (0.33) | FLT4 | |
| SCHEMBL7042064 | 0.84 | FLT4 (0.32) | FLT4 | |
| SCHEMBL7036150 | 0.74 | HRH3 (0.32) | — | |
| SCHEMBL7038464 | 0.71 | BMPR1B (0.30) | — | |
| SCHEMBL7037693 | 0.65 | CCNB2 (0.35) | FLT4 | |
| SCHEMBL12590714 | 0.63 | CTDSP1 (0.31) | — | |
| SCHEMBL7037511 | 0.63 | PDE5A (0.38) | — | |
| SCHEMBL18939407 | 0.62 | HPGD (0.48) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |