Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 10/20 | 0.35 |
| ▸ | CDK1 | P06493 | 10/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 10/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 10/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.35 |
| ▸ | FLT4 | P35916 | 3/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 7/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 4/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036895 | 0.88 | FLT4 (0.31) | FLT4 | |
| SCHEMBL7038464 | 0.74 | BMPR1B (0.30) | — | |
| SCHEMBL7039195 | 0.67 | FLT4 (0.40) | CDK1CCNB1FLT4MAP3K14 | |
| SCHEMBL6133993 | 0.66 | FFAR1 (0.36) | — | |
| SCHEMBL7038833 | 0.65 | HPGD (0.34) | FLT4 | |
| SCHEMBL23370058 | 0.65 | POLB (0.36) | — | |
| SCHEMBL6985198 | 0.64 | HSD11B1 (0.37) | — | |
| SCHEMBL6134011 | 0.64 | POLB (0.35) | — | |
| SCHEMBL7036150 | 0.62 | HRH3 (0.32) | — | |
| SCHEMBL8004896 | 0.62 | EDNRB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |