SCHEMBL7036006

SCHEMBL7036006

Cc1cc(F)ccc1NC(=O)c1ccc(CC(F)Cc2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR3 P32745 3/20 0.53
LMNA P02545 3/20 0.50
THRB P10828 1/20 0.50
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
TAS1R2 Q8TE23 1/20 0.46
RAB9A P51151 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
ALDH1A1 P00352 1/20 0.43
NR1I2 O75469 1/20 0.43
PPARG P37231 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
NR1H4 Q96RI1 1/20 0.42
HDAC1 Q13547 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7033732 0.87 SSTR3 (0.55) SSTR3LMNATHRBMAPTTP53
SCHEMBL8048026 0.80 SSTR3 (0.48) SSTR3LMNATHRBMAPTTP53
SCHEMBL7037133 0.75 CCR3 (0.46) SSTR3LMNAHDAC1CYP1A2CYP2C19
SCHEMBL9979393 0.72 CYP1A2 (0.55) LMNAMAPTTAS1R3TAS1R1TAS1R2
SCHEMBL7037898 0.72 LMNA (0.49) SSTR3LMNATHRBMAPTTP53
SCHEMBL6479806 0.71 HDAC1 (0.68) MAPTTP53RAB9AALDH1A1HDAC1
SCHEMBL7107214 0.71 PTPRG (0.43) NR1H4SMN1; SMN2GFER
SCHEMBL28857612 0.70 GAA (0.57) LMNATHRBMAPTTP53RAB9A
SCHEMBL19462130 0.70 HDAC1 (0.73) LMNAMAPTRAB9AALDH1A1L3MBTL1
SCHEMBL18160392 0.69 L3MBTL1 (0.59) THRBMAPTTP53TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2003-12-04 US claimed
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 2002-06-06 US claimed
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP claimed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO claimed
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2003-12-04 US disclosed
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 2002-06-06 US disclosed
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP disclosed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES CBR1, CBR3, CYP2E1 SSTR3 779/4885LMNA 1663/4885THRB 520/4885
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides CBR3, CBR1, CYP2E1 SSTR3 644/4885LMNA 1581/4885THRB 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.