Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5968682 | 0.76 | HPGD (0.33) | — | |
| Hydrochloric Acid SCHEMBL7647996 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7645679 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7645242 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7646990 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL717811 | 0.67 | GPR3 (0.34) | — | |
| SCHEMBL5969555 | 0.66 | — | — | |
| SCHEMBL5969262 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL717823 | 0.63 | SIGMAR1 (0.31) | — | |
| SCHEMBL8057462 | 0.57 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054910-B1 | IMPROVED OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6624254-B1 | Uniform distrbution by coupling, hydrolysis, neutralization, condensation, oxidation or hydrosilation; films, sheets, moldings | THE DOW CHEMICAL COMPANY | 2003-09-23 | — | — | US | disclosed |
| EP-1259556-A2 | IMPROVED SILANE FUNCTIONALIZED OLEFIN INTERPOLYMERS AND DERIVATIVES THEREOF | THE DOW CHEMICAL COMPANY (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6258902-B1 | USING A METAL COMPLEX CATALYST AND AN ALKENYL CONTAINING HYDROCARBYLSILANE | THE DOW CHEMICAL COMPANY | 2001-07-10 | — | — | US | disclosed |
| WO-2001009207-A2 | IMPROVED SILANE FUNCTIONALIZED OLEFIN INTERPOLYMERS AND DERIVATIVES THEREOF | THE DOW CHEMICAL COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |
| EP-1054910-A1 | IMPROVED OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041289-A1 | IMPROVED OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |