SCHEMBL7036675

SCHEMBL7036675

CC(C)c1c(O)cccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 4/20 0.48
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
CA1 P00915 4/20 0.39
CA2 P00918 4/20 0.39
CYP3A4 P08684 3/20 0.39
HPGD P15428 3/20 0.39
CA9 Q16790 2/20 0.39
ALOX15 P16050 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
TYR P14679 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MDM4 O15151 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
ALOX12 P18054 1/20 0.39
CA5A P35218 1/20 0.39
HTT P42858 1/20 0.39
HDAC4 P56524 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10012222 0.88 TSHR (0.52) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL19971983 0.84 TSHR (0.48) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL29558146 0.84 TSHR (0.48) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL725385 0.83 GABRA1 (0.52) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL279564 0.83 CYP1A2 (0.44) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL11302263 0.79 ALDH1A1 (0.46) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL19971985 0.79 TSHR (0.52) TSHRALDH1A1CA1CA2CYP3A4
SCHEMBL4760454 0.79 CYP3A4 (0.42) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL20845770 0.78 TSHR (0.42) TSHRALDH1A1GABRA1GABRB2CA1
SCHEMBL8749953 0.77 TSHR (0.50) TSHRALDH1A1CA1CA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN claimed
EP-1133504-B1 METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2003-03-12 EP claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-12466781-B2 Thyromimetics AUTOBAHN THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
WO-2024145245-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2024-07-04 WO disclosed
CN-112679635-B Preparation method of supported metallocene catalyst and catalyst prepared by preparation method 中国石油化工股份有限公司 2024-03-26 CN disclosed
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
US-20230048992-A1 NOVEL THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-02-16 US disclosed
US-20230048992-A1 NOVEL THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-02-16 US disclosed
CN-115279359-A Novel thyromimetic agents 速通医疗公司 2022-11-01 CN disclosed
WO-2022212296-A1 ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS D.E. SHAW RESEARCH, LLC (US) 2022-10-06 WO disclosed
US-20180177767-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC. (US) 2018-06-28 US disclosed
US-20180177767-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC. (US) 2018-06-28 US disclosed
US-20170022184-A1 SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF ARAXES PHARMA LLC 2017-01-26 US disclosed
US-20130096104-A1 IMIDAZOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE GENENTECH, INC. (US) 2013-04-18 US disclosed
WO-2011113802-A2 IMIDAZOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE F. HOFFMANN-LA ROCHE AG (CH) 2011-09-22 WO disclosed
US-4291177-A MIXTURES USEFUL FOR FUNGICIDES OR FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1981-09-22 US disclosed
US-4283566-A FUNGICIDES, FIRE RETARDANTS GENERAL ELECTRIC COMPANY (US) 1981-08-11 US disclosed
US-4275245-A MIXTURES OF CONTROLLED QUANTITIES FOR PRODUCING FIREPROOF POLYESTERS OR POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1981-06-23 US disclosed
US-4210765-A WITH SULFURYL CHLORIDE GENERAL ELECTRIC COMPANY (US) 1980-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096104-A1 IMIDAZOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE TYK2, IRAK1, IRAK4 TSHR 1070/4885ALDH1A1 4161/4885GABRA1 1485/4885
US-20230048992-A1 NOVEL THYROMIMETICS TSHR, TPO, CHRM1 TSHR 1/4885ALDH1A1 1048/4885GABRA1 3074/4885
US-12466781-B2 Thyromimetics TPO, TSHR, CHRM1 TSHR 2/4885ALDH1A1 1070/4885GABRA1 3097/4885
US-20180177767-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME KRAS, NRAS, HRAS TSHR 4359/4885ALDH1A1 4162/4885GABRA1 4420/4885
US-20170022184-A1 SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF KRAS, NRAS, HRAS TSHR 2950/4885ALDH1A1 2059/4885GABRA1 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.