SCHEMBL19971985

SCHEMBL19971985

Oc1cccc(Cl)c1C(Cl)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.38
EGFR P00533 2/20 0.38
CA2 P00918 2/20 0.38
FYN P06241 2/20 0.38
MMP9 P14780 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 2/20 0.38
RECQL P46063 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ADAMTS4 O75173 1/20 0.38
CA1 P00915 1/20 0.38
MMP2 P08253 1/20 0.38
MMP8 P22894 1/20 0.38
CA6 P23280 1/20 0.38
CDK2 P24941 1/20 0.38
MMP12 P39900 1/20 0.38
ADAMTS5 Q9UNA0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5368610 0.82 CYP1A2 (0.45) TSHRALDH1A1LMNATDP1CYP1A2
SCHEMBL10012222 0.81 TSHR (0.52) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL7036675 0.79 TSHR (0.50) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL8749953 0.79 TSHR (0.50) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL19971983 0.77 TSHR (0.48) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL29558146 0.77 TSHR (0.48) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL6656127 0.74 TRPA1 (0.50) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL29275470 0.73 PIM1 (0.35) TSHRALDH1A1LMNAEGFRCA2
SCHEMBL11302263 0.73 ALDH1A1 (0.46) TSHRALDH1A1LMNACA2HPGD
2-Chlorophenol SCHEMBL1357259 0.72 ALDH1A1 (0.83) TSHRALDH1A1LMNAEGFRCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406374-B Process for preparing 3-chloro-2-vinylphenyl sulfonate 拜耳作物科学股份公司 2020-07-14 CN claimed
US-10618872-B2 Process for preparing 3-chloro-2-vinylphenylsulfonates BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-04-14 US claimed
EP-3265439-B1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES BAYER CROPSCIENCE AG (DE) 2019-03-27 EP claimed
US-20180079717-A1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-22 US claimed
CN-107406374-A Process for preparing 3-chloro-2-vinylphenyl sulfonate 拜耳作物科学股份公司 2017-11-28 CN claimed
CN-107406374-B Process for preparing 3-chloro-2-vinylphenyl sulfonate 拜耳作物科学股份公司 2020-07-14 CN disclosed
US-10618872-B2 Process for preparing 3-chloro-2-vinylphenylsulfonates BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-04-14 US disclosed
EP-3265439-B1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES BAYER CROPSCIENCE AG (DE) 2019-03-27 EP disclosed
US-20180079717-A1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-22 US disclosed
CN-107406374-A Process for preparing 3-chloro-2-vinylphenyl sulfonate 拜耳作物科学股份公司 2017-11-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079717-A1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES AGPS, VARS1, VPS4B TSHR 4155/4885ALDH1A1 3434/4885LMNA 3617/4885
US-10618872-B2 Process for preparing 3-chloro-2-vinylphenylsulfonates AGPS, VARS1, VPS4B TSHR 4155/4885ALDH1A1 3434/4885LMNA 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.