Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL3141779 | 1.00 | SLC22A1 (0.67) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL9439997 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL19834900 | 0.97 | SLC22A1 (0.71) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL49814 | 0.97 | SLC22A1 (0.71) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL7638948 | 0.95 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28973535 | 0.94 | SLC22A1 (0.67) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL31067882 | 0.94 | SLC22A1 (0.67) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL29164920 | 0.94 | SLC22A1 (0.67) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28547695 | 0.94 | SLC22A1 (0.67) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL3795562 | 0.94 | SLC22A1 (0.67) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605578-A2 | ELECTROCATALYTIC GENERATION OF IMINES FROM ALCOHOLS AND AMINES | Université Paris Cité (FR) | 2025-08-27 | — | — | EP | claimed |
| CN-119980324-A | Preparation method of iron-based composite anode and application of iron-based composite anode in electrochemical synthesis of adiponitrile | 万华化学集团股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119246849-B | Kit for detecting heart injury of dogs and application | 上海基灵生物科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-117209330-B | Special intelligent controlled-release fertilizer for corn and preparation method thereof | 山东农业大学 | 2025-02-07 | — | — | CN | claimed |
| CN-119246849-A | Kit for detecting heart injury of dogs and application | 上海基灵生物科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| US-20240343757-A1 | PROCESS FOR THE PREPARATION OF BUDESONIDE 21-PHOSPHATE | GENETIC S.P.A. (IT) | 2024-10-17 | — | — | US | claimed |
| CN-118150724-A | Analysis method for detecting organic impurities in propranolol hydrochloride drops | 成都利尔药业有限公司 | 2024-06-07 | — | — | CN | claimed |
| EP-4373833-A1 | PROCESS FOR THE PREPARATION OF BUDESONIDE 21-PHOSPHATE | Genetic S.p.A. (IT) | 2024-05-29 | — | — | EP | claimed |
| CN-118027047-A | Preparation method of sandy midbody | 西安交通大学 | 2024-05-14 | — | — | CN | claimed |
| WO-2024083554-A2 | ELECTROCATALYTIC GENERATION OF IMINES FROM ALCOHOLS AND AMINES | UNIVERSITE PARIS CITE (FR) | 2024-04-25 | — | — | WO | claimed |
| WO-2005007084-A2 | PANCRATISTATIN CYCLIC PHOSPHATE PRODRUGS AN PHENPANSTATIN CYCLIC PHOSPHATE PRODRUGS | ARIZONA BOARD OF REGENTS A BODY CORPORATE OF THE STATE OF ARIZONE, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2005-01-27 | — | — | WO | claimed |
| US-20040127461-A1 | Water soluble, randomly substituted partial N-, partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof | ADJUVANT PHARMACEUTICALS, LLC (US) | 2004-07-01 | — | — | US | claimed |
| EP-1425310-A2 | WATER SOLUBLE, RANDOMLY SUBSTITUTED PARTIAL N-, PARTIAL O-ACETYLATED CHITOSAN, PRESERVING COMPOSITIONS CONTAINING CHITOSAN, AND PROCESSES FOR MAKING THEREOF | Technology Resource International Corporation (US) | 2004-06-09 | — | — | EP | claimed |
| US-6716970-B2 | CONTACT LENS PRESERVATIVE SOLUTION | ADJUVANT PHARMACEUTICALS, LLC | 2004-04-06 | — | — | US | claimed |
| US-20020177577-A1 | Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof | ADJUVANT PHARMACEUTICALS, LLC | 2002-11-28 | — | — | US | claimed |
| WO-2002085951-A2 | WATER SOLUBLE, RANDOMLY SUBSTITUTED PARTIAL N-, PARTIAL O-ACETYLATED CHITOSAN, PRESERVING COMPOSITIONS CONTAINING CHITOSAN, AND PROCESSES FOR MAKING THEREOF | TECHNOLOGY RESOURCE INTERNATIONAL CORPORATION (US) | 2002-10-31 | — | — | WO | claimed |
| US-20020018732-A1 | Preserving compositions containing chitosan and processes for making water soluble O-acetylated chitosan and chitosan | TECHNOLOGY RESOURCE INTERNATIONAL CORPORATION | 2002-02-14 | — | — | US | claimed |
| EP-0877298-B1 | Coated xerographic photographic paper | XEROX CORP (US) | 2001-08-29 | — | — | EP | claimed |
| US-5846637-A | Coated xerographic photographic paper | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| EP-0877298-A2 | Coated xerographic photographic paper | Xerox Corporation (US) | 1998-11-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177577-A1 | Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof | PIGS, CSGALNACT1, OGA | ADRA1A 4392/4885KCNH2 1429/4885SLC22A1 3151/4885 |
| US-20240343757-A1 | PROCESS FOR THE PREPARATION OF BUDESONIDE 21-PHOSPHATE | CYP4A11, CYP11B1, HSD11B1 | ADRA1A 320/4885KCNH2 4671/4885SLC22A1 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.