Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030589 | 0.80 | ALDH1A1 (0.33) | LMNAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6569258 | 0.80 | CACNA1F (0.48) | LMNACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9526526 | 0.79 | ALDH1A1 (0.40) | LMNACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7080536 | 0.74 | ALDH1A1 (0.49) | LMNACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9524891 | 0.72 | TSHR (0.37) | LMNACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL8692056 | 0.69 | ADORA3 (0.37) | LMNACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9510806 | 0.69 | ALDH1A1 (0.36) | LMNACACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL25199116 | 0.67 | LMNA (0.44) | LMNAALDH1A1HTT | |
| SCHEMBL16009163 | 0.67 | ALDH1A1 (0.42) | LMNAALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL25194063 | 0.66 | LMNA (0.39) | LMNAALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286974-A2 | MEDICAMENT FOR VIRAL DISEASES | Bayer Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002020509-A2 | MEDICAMENTS AGAINST VIRAL INFECTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| WO-2001064755-A2 | ISOXAZOLE GEGEN VIRALE ERKRANKUNGEN | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-07 | — | — | WO | disclosed |