Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 11/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911535 | 0.87 | MAPT (0.58) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL28810314 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| Hydrochloric Acid SCHEMBL3419672 | 0.81 | MAPT (0.60) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL7037581 | 0.81 | MAPT (0.68) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL11842385 | 0.79 | RAB9A (0.57) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL11838962 | 0.79 | MAPT (0.60) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL11295618 | 0.79 | MAPT (0.68) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL430629 | 0.79 | MAPT (0.59) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL20984284 | 0.78 | RAB9A (0.60) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4233854 | 0.78 | HCAR3 (0.60) | SMN1; SMN2MAPTRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | TEIJIN LIMITED (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1167360-A9 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1167360-A1 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | CMA1, CTRL, CPA4 | SMN1; SMN2 3328/4885MAPT 3505/4885RAB9A 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.