Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475988 | 0.93 | PLAU (0.47) | PLAUGSK3BKAT6AXDHSLC22A12 | |
| SCHEMBL7043151 | 0.88 | PLAU (0.47) | PLAUGSK3BKAT6AXDHSLC22A12 | |
| SCHEMBL7822720 | 0.83 | PLAU (0.61) | PLAUGSK3BKAT6AXDHSLC22A12 | |
| SCHEMBL7717556 | 0.82 | PLAU (0.50) | PLAUKAT6AXDHSLC22A12EGLN1 | |
| SCHEMBL6749963 | 0.81 | CYP4F2 (0.48) | PLAUGSK3BKAT6AXDHSLC22A12 | |
| SCHEMBL6288448 | 0.79 | PLAU (0.47) | PLAUKAT6AXDHSLC22A12EGLN1 | |
| SCHEMBL6751413 | 0.79 | PLAU (0.47) | PLAUKAT6AXDHSLC22A12EGLN1 | |
| SCHEMBL6659038 | 0.79 | PLAU (0.60) | PLAUKAT6AXDHSLC22A12ADAMTS4 | |
| SCHEMBL7031551 | 0.79 | MCHR1 (0.43) | PLAUGSK3BKAT6ALIPGIKBKB | |
| SCHEMBL6753784 | 0.78 | LOXL2 (0.53) | PLAUKAT6AXDHSLC22A12EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203935-A1 | Cyanobiphenyl derivatives | TEIJIN LIMITED | 2003-10-30 | — | — | US | disclosed |
| US-6538137-B1 | Blood-coagulation factor X inhibitors | TEIJIN LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1179527-A1 | CYANOBIPHENYL DERIVATIVES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203935-A1 | Cyanobiphenyl derivatives | F9, F12, F11 | PLAU 111/4885GSK3B 2745/4885KAT6A 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.