Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751413 | 0.89 | PLAU (0.47) | CYP4F2CYP4A11PLAUMRGPRX4KAT6A | |
| SCHEMBL6753784 | 0.88 | LOXL2 (0.53) | CYP4F2CYP4A11PLAUMRGPRX4KAT6A | |
| SCHEMBL7663246 | 0.84 | MRGPRX4 (0.48) | PLAUMRGPRX4KAT6ALOXL2XDH | |
| SCHEMBL7662548 | 0.84 | MRGPRX4 (0.51) | PLAUMRGPRX4KAT6A | |
| SCHEMBL7714047 | 0.84 | MRGPRX4 (0.51) | PLAUMRGPRX4KAT6AEGLN1 | |
| SCHEMBL7656098 | 0.83 | MRGPRX4 (0.45) | CYP4F2CYP4A11PLAUMRGPRX4KAT6A | |
| SCHEMBL7822720 | 0.83 | PLAU (0.61) | PLAUMRGPRX4GSK3BKAT6ALOXL2 | |
| SCHEMBL7717556 | 0.82 | PLAU (0.50) | PLAUMRGPRX4KAT6AEGLN1XDH | |
| SCHEMBL7656101 | 0.82 | PLAU (0.42) | CYP4F2CYP4A11PLAUMRGPRX4KAT6A | |
| SCHEMBL7240867 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11LOXL2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043310-B1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LTD (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-6706745-B1 | THERAPY FOR ANTICOAGULATION PLAYS AN IMPORTANT PART IN THE MEDICAL TREATMENT AND PROPHYLAXIS OF THROMBOEMBOLISMS | TEIJIN LIMITED (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20030203935-A1 | Cyanobiphenyl derivatives | TEIJIN LIMITED | 2003-10-30 | — | — | US | disclosed |
| US-6538137-B1 | Blood-coagulation factor X inhibitors | TEIJIN LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1179527-A1 | CYANOBIPHENYL DERIVATIVES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1043310-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203935-A1 | Cyanobiphenyl derivatives | F9, F12, F11 | CYP4F2 245/4885CYP4A11 1447/4885PLAU 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.