Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 5/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856931 | 0.84 | TRIM24 (0.52) | ERN1KAT6AXDHSLC22A12IKBKB | |
| SCHEMBL7822720 | 0.84 | PLAU (0.61) | PLAUERN1KAT6AXDHSLC22A12 | |
| SCHEMBL7717556 | 0.83 | PLAU (0.50) | PLAUERN1SIRT5KAT6AXDH | |
| SCHEMBL29929690 | 0.81 | ERN1 (0.63) | PLAUERN1ALDH1A1CA12CA1 | |
| SCHEMBL10068712 | 0.81 | ALDH1A1 (0.53) | ERN1ALDH1A1CA12CA1CA2 | |
| SCHEMBL6751413 | 0.80 | PLAU (0.47) | PLAUSIRT5KAT6AXDHSLC22A12 | |
| SCHEMBL6659038 | 0.80 | PLAU (0.60) | PLAUERN1SIRT5KAT6AXDH | |
| SCHEMBL2160688 | 0.80 | ALDH1A1 (0.50) | ERN1ALDH1A1XDHP4HBCYP11B1 | |
| SCHEMBL6749963 | 0.79 | CYP4F2 (0.48) | PLAUERN1SIRT5KAT6AXDH | |
| SCHEMBL7038355 | 0.79 | PLAU (0.47) | PLAUERN1SIRT5KAT6AXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949668-B2 | Process for producing 5-(3-cyanophenyl)-3-formylbenzoic acid compound | TEIJIN LIMITED (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20050014966-A1 | Process for producing 5-(3-cyanophenyl)-3-formylbenzoic acid compound | TEIJIN LIMITED (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1460059-A1 | PROCESS FOR PRODUCING 5-(3-CYANOPHENYL)-3-FORMYLBENZOIC ACID COMPOUND | TEIJIN LIMITED (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040072866-A1 | Process for preparation of cyanophenylbenzoic acid derivatives | TEIJIN LIMITED (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1361213-A1 | PROCESS FOR PREPARATION OF CYANOPHENYLBENZOIC ACID DERIVATIVES | TEIJIN LIMITED (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-20030203935-A1 | Cyanobiphenyl derivatives | TEIJIN LIMITED | 2003-10-30 | — | — | US | disclosed |
| US-6538137-B1 | Blood-coagulation factor X inhibitors | TEIJIN LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1179527-A1 | CYANOBIPHENYL DERIVATIVES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072866-A1 | Process for preparation of cyanophenylbenzoic acid derivatives | CCNY, ACLY, IWS1 | PLAU 3848/4885ERN1 1737/4885SIRT5 410/4885 |
| US-20050014966-A1 | Process for producing 5-(3-cyanophenyl)-3-formylbenzoic acid compound | PAH, CA5B, PCCA | PLAU 2817/4885ERN1 4692/4885SIRT5 487/4885 |
| US-20030203935-A1 | Cyanobiphenyl derivatives | F9, F12, F11 | PLAU 111/4885ERN1 1752/4885SIRT5 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.