Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6290918 | 0.90 | MLYCD (0.37) | TP53KLK1KLK5ALDH1A1ABCC9 | |
| Trifluoroacetic Acid SCHEMBL6287794 | 0.90 | MLYCD (0.37) | TP53KLK1KLK5ALDH1A1ABCC9 | |
| Trifluoroacetic Acid SCHEMBL7039259 | 0.88 | GABRB1 (0.40) | F2NPC1RAB9ATMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7039294 | 0.83 | KLK1 (0.39) | TP53HTTP2RX1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL6286326 | 0.83 | NR1H4 (0.37) | KLK1KLK5F2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6287884 | 0.81 | KEAP1 (0.37) | KLK1KLK5MAPK1KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6286281 | 0.79 | CES1 (0.39) | TP53GAANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6288018 | 0.79 | CES1 (0.39) | TP53GAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6286600 | 0.78 | CHRNA1 (0.37) | KLK1KDM4ENLRP3 | |
| SCHEMBL6290435 | 0.77 | EGFR (0.34) | KLK1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | TP53 3089/4885GAA 4704/4885HTT 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.