Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359518 | 0.87 | VNN1 (0.45) | GAACTBP2VNN1TDP1POLB | |
| SCHEMBL1151049 | 0.83 | GAA (0.50) | GAACTBP2VNN1TDP1POLB | |
| SCHEMBL526194 | 0.83 | GAA (0.57) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL4645956 | 0.82 | GAA (0.50) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL12731522 | 0.82 | GAA (0.48) | GAACTBP2VNN1TDP1POLB | |
| SCHEMBL28221360 | 0.81 | GAA (0.52) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL8833730 | 0.80 | TDP1 (0.56) | GAACTBP2VNN1TDP1POLB | |
| SCHEMBL28154639 | 0.80 | TAAR1 (0.48) | GAACTBP2VNN1TDP1POLB | |
| SCHEMBL6935977 | 0.80 | L3MBTL1 (0.61) | GAACTBP2VNN1TDP1SMN1; SMN2 | |
| SCHEMBL5572550 | 0.79 | L3MBTL1 (0.55) | GAACTBP2TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286786-A2 | SPREADABLE ADHESIVE COMPOSITIONS AND APPLICATORS FOR USE THEREWITH | Loctite (R & D) Limited (IE) | 2003-03-05 | — | — | EP | disclosed |
| EP-1235831-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001091915-A2 | SPREADABLE ADHESIVE COMPOSITIONS AND APPLICATORS FOR USE THEREWITH | LOCTITE (R & D) LIMITED (IE) | 2001-12-06 | — | — | WO | disclosed |
| WO-2001028992-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | disclosed |
| EP-0099148-A1 | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them | GIST-BROCADES N.V. (NL) | 1984-01-25 | — | — | EP | disclosed |