SCHEMBL7040136

SCHEMBL7040136

Cc1ccc(C(=O)Cc2ccccc2)cc1C

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
MAPT P10636 1/20 0.56
SRD5A2 P31213 2/20 0.54
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
PLAU P00749 1/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 2/20 0.54
GRM1 Q13255 1/20 0.54
ALDH1A1 P00352 1/20 0.51
RECQL P46063 1/20 0.49
PSMB8 P28062 2/20 0.49
PSMB5 P28074 2/20 0.49
GAA P10253 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4296416 0.86 LMNA (0.56) L3MBTL1MAPTSRD5A2RAB9ANPC1
SCHEMBL15197228 0.85 GRM1 (0.60) L3MBTL1MAPTSRD5A2RAB9ANPC1
SCHEMBL6284274 0.83 CCNC (0.51) CES2CES1L3MBTL1MAPTRAB9A
SCHEMBL257535 0.82 NPC1 (0.53) L3MBTL1MAPTSRD5A2RAB9ANPC1
SCHEMBL6204532 0.82 TAS1R3 (0.56) L3MBTL1MAPTSRD5A2RAB9ANPC1
SCHEMBL15191689 0.82 PIK3CA (0.51) CES2CES1L3MBTL1MAPTRAB9A
SCHEMBL1555065 0.82 KMT2A (0.54) CES2CES1L3MBTL1MAPTSRD5A2
SCHEMBL13400965 0.82 MEN1 (0.45) CES2CES1L3MBTL1MAPTRAB9A
SCHEMBL7129800 0.80 MAPT (0.80) CES2CES1L3MBTL1MAPTSRD5A2
SCHEMBL14982170 0.80 KMT2A (0.67) CES2CES1L3MBTL1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9805707-B2 Sound absorbing and insulating material and method for manufacturing the same HYUNDAI MOTOR COMPANY (KR) 2017-10-31 US disclosed
US-20170032776-A1 SOUND ABSORBING AND INSULATING MATERIAL AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR COMPANY (KR) 2017-02-02 US disclosed
US-20160300560-A1 SOUND ABSORBING AND INSULATING MATERIAL AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR COMPANY (KR) 2016-10-13 US disclosed
US-8895552-B2 Cyclic amide derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2014-11-25 US disclosed
US-8821617-B2 Polyimide-co-polybenzoxazole copolymer, preparation method thereof, and gas separation membrane comprising the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2014-09-02 US disclosed
US-8642722-B2 Preparation method of polybenzimidazole IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2014-02-04 US disclosed
US-20130217692-A1 CYCLIC AMIDE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2013-08-22 US disclosed
US-8487064-B2 Polymer compounds and a preparation method thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2013-07-16 US disclosed
US-8232367-B2 Polymer compounds and a preparation method thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2012-07-31 US disclosed
US-8163071-B2 Hollow fiber, dope composition for forming hollow fiber, and method of preparing hollow fiber using the same IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2012-04-24 US disclosed
US-20120042777-A1 GAS SEPARATION USING MEMBRANES COMPRISING POLYBENZOXAZOLES PREPARED BY THERMAL REARRANGEMENT INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2012-02-23 US disclosed
US-20110230605-A1 Polymer compounds and a preparation method thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2011-09-22 US disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
US-20110009506-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2011-01-13 US disclosed
EP-0659737-B1 Catecholamine surrogates useful as beta 3 agonists BRISTOL MYERS SQUIBB CO (US) 2003-03-26 EP disclosed
US-5776983-A ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-07-07 US disclosed
EP-0659737-A2 Catecholamine surrogates useful as B3 agonists BRISTOL-MYERS SQUIBB COMPANY (US) 1995-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130217692-A1 CYCLIC AMIDE DERIVATIVE HDAC10, H1-10, H1-0 CES2 420/4885CES1 811/4885L3MBTL1 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.