Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.34 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407197 | 0.91 | TOP2A (0.46) | TDP2S100A4CDC25BTOP2AHKDC1 | |
| SCHEMBL6866894 | 0.86 | KMT2A (0.41) | TDP2MEN1THRBBLMKMT2A | |
| SCHEMBL6408056 | 0.84 | TOP2A (0.36) | KMT2ATOP2AHKDC1 | |
| SCHEMBL6410307 | 0.78 | MAOA (0.38) | TDP2KMT2ATDP1TOP2AHKDC1 | |
| SCHEMBL7040428 | 0.78 | MEN1 (0.42) | TDP2MEN1THRBBLMKMT2A | |
| SCHEMBL6865737 | 0.77 | TDP2 (0.51) | TDP2 | |
| SCHEMBL6863937 | 0.76 | TOP2A (0.50) | TDP2MEN1THRBBLMKMT2A | |
| SCHEMBL6411062 | 0.75 | MEN1 (0.47) | TDP2MEN1THRBBLMKMT2A | |
| SCHEMBL6409081 | 0.74 | HKDC1 (0.46) | TDP2MEN1THRBBLMKMT2A | |
| Iodide SCHEMBL6859932 | 0.74 | MEN1 (0.46) | TDP2MEN1THRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202993-B1 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LAFON LABOR (FR) | 2005-10-19 | — | — | EP | claimed |
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | claimed |
| EP-1202993-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | claimed |
| WO-2001012632-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | claimed |
| EP-1202993-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001012632-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | disclosed |