Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY4R | P50391 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526076 | 0.90 | BMP1 (0.39) | HDAC6HDAC1F2F10PRSS1 | |
| SCHEMBL8526765 | 0.89 | F10 (0.45) | PPARGF2F10PRSS1 | |
| SCHEMBL8121972 | 0.89 | TRPM8 (0.38) | PPARGTRPM8HDAC8MEN1KMT2A | |
| SCHEMBL7039830 | 0.85 | MAOA (0.39) | NPY1RNPY4RNPY5R | |
| SCHEMBL8525743 | 0.80 | F10 (0.39) | F2F10PRSS1 | |
| SCHEMBL8525704 | 0.79 | F10 (0.44) | F2F10PRSS1PLAU | |
| SCHEMBL8121716 | 0.79 | SLC6A4 (0.43) | PPARGTRPM8MEN1KMT2A | |
| SCHEMBL8529359 | 0.79 | NPY1R (0.37) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL6900983 | 0.78 | PRSS1 (0.41) | TRPM8F2F10PRSS1MEN1 | |
| SCHEMBL7058207 | 0.78 | PRSS1 (0.41) | TRPM8F2F10PRSS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |