Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037673 | 0.84 | CHRM1 (0.45) | ALDH1A1KDM4ECHRM1CHRM3 | |
| SCHEMBL22699087 | 0.79 | KMT2A (0.61) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL20343486 | 0.77 | LMNA (0.44) | LMNAMAPK1CHRM1HSD17B10CHRM3 | |
| SCHEMBL27225773 | 0.77 | KDM4E (0.66) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL11028736 | 0.73 | ACE (0.55) | ALDH1A1KDM4EGAALMNAHSD17B10 | |
| SCHEMBL21383627 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL13429539 | 0.73 | GAA (0.65) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL21484989 | 0.73 | EPHX2 (0.53) | GAA | |
| SCHEMBL10347147 | 0.72 | HRH3 (0.51) | ALDH1A1KDM4EGAA | |
| SCHEMBL9352454 | 0.71 | ACE (0.43) | ALDH1A1GAATSHRMAPK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037637-B1 | USE OF 5HT1A RECEPTOR ANTAGONISTS FOR PREVENTING AND/OR TREATING TEMPORAL LOBE EPILEPSY | UNIV PRINCETON (US) | 2003-03-19 | — | — | EP | disclosed |