SCHEMBL7041998

SCHEMBL7041998

COC=Cc1c(Cl)ccc(C(=O)C2C(=O)CCCC2=O)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.34
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7655601 0.77 TSHR (0.41) MAPK1
SCHEMBL10376030 0.76 HPD (0.42) HPD
SCHEMBL8139938 0.76 ABL1 (0.41)
SCHEMBL8139935 0.76 ABL1 (0.41)
SCHEMBL6449853 0.71 PKM (0.41) HPD
SCHEMBL7174222 0.71 HPD (0.33) HPD
SCHEMBL3436992 0.71 SLC6A3 (0.33) HPD
SCHEMBL2902825 0.70 HPD (0.36) HPD
SCHEMBL9134805 0.69 HPD (0.37) HPD
SCHEMBL10192440 0.69 MAPK1 (0.46) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984914-B1 SUBSTITUTED 2-(3-ALKENYL-BENZOYL)-CYCLOHEXANE-1,3-DIONES BASF AG (DE) 2003-03-19 EP disclosed
US-6372693-B1 AGRICULTURAL HERBICIDES FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed