SCHEMBL7042333

SCHEMBL7042333

CCOc1nn(-c2cccc(OCCN(CC)CC)c2)c(=O)o1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.67
BCHE P06276 1/20 0.66
LIPC P11150 1/20 0.66
ACHE P22303 1/20 0.66
LIPE Q05469 1/20 0.66
KDM4E B2RXH2 1/20 0.45
TSHR P16473 1/20 0.45
MAPT P10636 1/20 0.43
CHRNA7 P36544 1/20 0.43
KMT2A Q03164 1/20 0.43
GALR3 O60755 1/20 0.43
SIGMAR1 Q99720 2/20 0.43
ABHD16A O95870 1/20 0.42
KCNH2 Q12809 1/20 0.41
MCHR1 Q99705 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
TOP1 P11387 1/20 0.41
FAAH O00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7046440 0.81 MGLL (0.65) MGLLBCHELIPCACHELIPE
SCHEMBL6552675 0.80 MGLL (1.00) MGLLBCHELIPCACHELIPE
SCHEMBL6552559 0.80 BCHE (1.00) MGLLBCHELIPCACHELIPE
SCHEMBL7044396 0.78 MGLL (0.71) MGLLBCHELIPCACHELIPE
SCHEMBL2233786 0.76 MGLL (0.76) MGLLBCHELIPCACHELIPE
SCHEMBL2702514 0.73 MGLL (0.60) MGLLBCHELIPCACHELIPE
SCHEMBL9706141 0.72 KDM4E (0.73) KDM4ETSHRMAPTCHRNA7KMT2A
SCHEMBL2702372 0.71 BCHE (0.78) MGLLBCHELIPCACHELIPE
SCHEMBL2702338 0.70 MGLL (0.55) MGLLBCHELIPCACHELIPE
SCHEMBL7044238 0.69 BCHE (0.81) MGLLBCHELIPCACHELIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase AVENTIS PHARMA DEUTSCHLAND GMBH 2003-12-25 US disclosed
US-6596742-B1 Inhibitory effect on the hormone-sensitive lipase, HSL. insecticides, controlling metabolism and multistage synthesis AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase PNLIP, CEL, LIPE MGLL 10/4885BCHE 626/4885LIPC 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.