Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725821 | 0.95 | ALDH1A1 (0.54) | RAB9ANPC1PKMTSHRCTNNB1 | |
| SCHEMBL2394331 | 0.78 | NPC1 (0.69) | RAB9ANPC1PKMTSHRCTNNB1 | |
| SCHEMBL6725021 | 0.76 | NPC1 (0.47) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL619634 | 0.74 | MAPK1 (0.78) | RAB9ANPC1PKMTSHRCTNNB1 | |
| SCHEMBL4828375 | 0.73 | NPC1 (0.70) | RAB9ANPC1PKMTSHRCTNNB1 | |
| Formaldehyde SCHEMBL27289523 | 0.71 | MAPK1 (0.72) | RAB9ANPC1PKMTSHRCTNNB1 | |
| SCHEMBL653025 | 0.71 | PKM (0.87) | PKMTSHRCTNNB1ATMALDH1A1 | |
| SCHEMBL2393677 | 0.71 | NPC1 (0.65) | RAB9ANPC1TSHRCTNNB1ATM | |
| SCHEMBL2806009 | 0.70 | KDM4E (0.72) | RAB9ANPC1PKMTSHRCTNNB1 | |
| SCHEMBL2807412 | 0.70 | KDM4E (0.72) | RAB9ANPC1PKMTSHRCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |