Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611650 | 0.81 | ADRB3 (0.58) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL11226581 | 0.80 | SLC6A2 (0.66) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL7250507 | 0.78 | ADRB3 (0.61) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL7042586 | 0.78 | ADRB3 (0.55) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL7042688 | 0.77 | ADRB2 (0.45) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL7042479 | 0.77 | ADRB2 (0.50) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL9054230 | 0.75 | ADRB3 (0.70) | ADRB2ADRB1ADRB3CYP2D6CYP1A2 | |
| SCHEMBL7638769 | 0.74 | ADRB3 (0.71) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7039636 | 0.74 | HIF1A (0.54) | ADRB2ADRB1SLC6A2PTGS1ADRB3 | |
| SCHEMBL9054228 | 0.74 | ADRB2 (0.61) | ADRB2ADRB1SLC6A2PTGS1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292564-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001062705-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-30 | — | — | WO | disclosed |