Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226581 | 0.81 | SLC6A2 (0.66) | HIF1ASLC6A2CYP2D6SLC6A4ADRA1A | |
| SCHEMBL7245557 | 0.77 | ADRB3 (0.56) | SLC6A2MEN1KMT2APTGS1ADRB2 | |
| SCHEMBL7039632 | 0.76 | ADRB3 (0.55) | SLC6A2PTGS1ADRB2ADRB3ADRB1 | |
| SCHEMBL11094669 | 0.76 | ADRB2 (0.64) | SLC6A2CYP2D6ADRA1APTGS1ADRB2 | |
| SCHEMBL7042590 | 0.74 | ADRB2 (0.56) | HIF1ASLC6A2CYP2D6SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL6320463 | 0.74 | KMT2A (0.55) | CYP2D6MEN1KMT2AADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL6320467 | 0.74 | KMT2A (0.55) | CYP2D6MEN1KMT2AADRB2ADRB3 | |
| SCHEMBL7556528 | 0.72 | CHRNB2 (0.50) | ADRB2ADRB3ADRB1LMNA | |
| SCHEMBL30566059 | 0.71 | LMNA (0.61) | LMNA | |
| SCHEMBL27575925 | 0.71 | LMNA (0.61) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292564-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001062705-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-30 | — | — | WO | disclosed |