Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043397 | 0.88 | CNR1 (0.58) | SMN1; SMN2RAB9ANPC1HPGDCYP2C19 | |
| SCHEMBL7046180 | 0.88 | EPHX2 (0.50) | SMN1; SMN2RAB9ANPC1HPGDTP53 | |
| SCHEMBL7044623 | 0.81 | NPC1 (0.43) | SMN1; SMN2RAB9ANPC1HPGDTP53 | |
| SCHEMBL6552063 | 0.79 | CNR1 (0.46) | TP53POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7044713 | 0.78 | RXFP1 (0.41) | SMN1; SMN2RAB9ANPC1HPGDTP53 | |
| SCHEMBL7042640 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1HPGDTP53 | |
| SCHEMBL7048220 | 0.74 | L3MBTL1 (0.53) | SMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL7044700 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1HPGDTP53 | |
| SCHEMBL7044205 | 0.73 | CNR1 (0.52) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL7042653 | 0.73 | CYP2D6 (0.53) | SMN1; SMN2RAB9ANPC1CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |