Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045001 | 0.88 | SMN1; SMN2 (0.42) | L3MBTL1GAANPC1POLBSMN1; SMN2 | |
| SCHEMBL7044697 | 0.79 | RHEB (0.45) | NPC1POLBSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7046457 | 0.77 | ALOX15 (0.48) | CNR1L3MBTL1CYP1A2POLBRXFP1 | |
| SCHEMBL7042512 | 0.76 | CNR1 (0.58) | CNR1NPC1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL7043397 | 0.76 | CNR1 (0.58) | CNR1KMT2AL3MBTL1NPC1MEN1 | |
| SCHEMBL7044623 | 0.74 | NPC1 (0.43) | CNR1L3MBTL1GAANPC1POLB | |
| SCHEMBL7041750 | 0.72 | CNR1 (0.44) | CNR1KMT2AALPLNPC1 | |
| SCHEMBL4079971 | 0.71 | CNR1 (0.59) | MAPTCNR1ALPLSMN1; SMN2LMNA | |
| SCHEMBL7042642 | 0.71 | ALOX5 (0.57) | MAPTKMT2AL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL7044713 | 0.69 | RXFP1 (0.41) | L3MBTL1GAANPC1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |